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Adiponectin receptor 1 Monoclonal antibody

Adiponectin receptor 1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human and More (3)

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1F12B3

Cat no : 66619-1-Ig

Synonyms

ACDCR1, Adiponectin receptor 1, Adiponectin receptor protein 1, ADIPOR1, CGI 45, CGI45, PAQR1, TESBP1A



Tested Applications

Positive WB detected inHeLa cells, HEK-293 cells, L02 cells, HepG2 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 6 publications below

Product Information

66619-1-Ig targets Adiponectin receptor 1 in WB, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Cited Reactivityhuman, mouse, pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Adiponectin receptor 1 fusion protein Ag18187 相同性解析による交差性が予測される生物種
Full Name adiponectin receptor 1
Calculated molecular weight 375 aa, 43 kDa
Observed molecular weight 43 kDa
GenBank accession numberBC010743
Gene symbol ADIPOR1
Gene ID (NCBI) 51094
RRIDAB_2881979
Conjugate Unconjugated
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin (ADIPOR1 and ADIPOR2) have been identified. They mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. The human ADIPOR1 gene maps to chromosome 1q32.1, and encodes a 375-amino acid protein with a molecular weight of 43 kDa. This antibody was raised against 1-72aa of human AdipoR1.

Protocols

Product Specific Protocols
WB protocol for Adiponectin receptor 1 antibody 66619-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Food Funct

A flavonoid-rich Smilax china L. extract prevents obesity by upregulating the adiponectin-receptor/AMPK signalling pathway and modulating the gut microbiota in mice.

Authors - Xin Li
mouseWB

Food Funct

Quercetin regulates skeletal muscle fiber type switching via adiponectin signaling.

Authors - Xiaoling Chen
humanWB

Biol Open

A stem cell based in vitro model of NAFLD enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference.

Authors - Nina Graffmann
pigWB

Anim Biotechnol

Leucine regulates porcine muscle fiber type transformation via adiponectin signaling pathway.

Authors - Lu Xiang
pigWB

Anim Biotechnol

Effect of dietary leucine supplementation on skeletal muscle fiber type transformation in weaning piglets

Authors - Xiaoling Chen
mouseWB

J Agric Food Chem

Probiotic Yogurt Alleviates High-Fat Diet-Induced Lipid Accumulation and Insulin Resistance in Mice via the Adiponectin Pathway

Authors - Chao Tang