calreticulin 抗体 10 文献

Rabbit Polyclonal| カタログ番号: 10292-1-AP

注目製品 KD/KO 検証済

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43,900円

(希望販売価格)

容量: 56 μg/150 μl

Choose quantity:

販売および在庫状況はコスモ・バイオ(株)にお問い合わせください。
distributor

種特異性:
human, mouse, rat

WB ポジティブ:
NIH/3T3 cells, HeLa cells, HL-60 cells, rat brain tissue, MCF-7 cells, COLO 320 cells, human skeletal muscle tissue, mouse brain tissue

IHC ポジティブ:
human thyroid tissue, human colon cancer tissue, human ovary tumor tissue, human skeletal muscle tissue

IF ポジティブ:
NIH/3T3 cells

推奨希釈倍率:
WB : 1:500-1:1000
IHC : 1:50-1:500
IF : 1:20-1:200

製品情報


由来:
Rabbit

精製方法:
Antigen affinity purification

アイソタイプ:
IgG

バッファー/保存方法:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.

ターゲット情報


正式名:
calreticulin

計算分子量:
60 kDa

検出分子量:
60 kDa

GenBank accession number:

Gene ID (NCBI):

遺伝子シンボル:
CALR

別名:
CALR, Calregulin, calreticulin, cC1qR, CRP55, CRT, CRTC, ERp60, grp60, HACBP, RO, SSA
背景説明

CALR,also named as grp60, ERp60, HACBP, CRP55, CRTC and Calregulin, belongs to the calreticulin family. It is a molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. CALR is a ER marker. It interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. CALR interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. The MW of CALR migrates aberrantly at 60 kD by SDS-PAGE. Some study provided that it's a new possibility for CRT-mediated tumor immune prevention and treatment.


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