GRP78/BIP 抗体 68 文献

Rabbit Polyclonal| カタログ番号: 11587-1-AP

注目製品 KD/KO 検証済

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43,900円

(希望販売価格)

容量: 86 μg/150 μl

Choose quantity:

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distributor

種特異性:
human, mouse, rat, Hamster, zebrafish

WB ポジティブ:
BxPC-3 cells, MCF-7 cells, TN treated Hela, mouse liver tissue, HeLa cells, mouse testis tissue, rat liver tissue

IP ポジティブ:
MCF-7 cells

IHC ポジティブ:
human pancreas cancer tissue, human breast cancer tissue,mouse heart tissue,human brain tissue,human colon cancer tissue

IF ポジティブ:
HepG2 cells

FC ポジティブ:
HeLa cells

推奨希釈倍率:
WB : 1:3000-1:8000
IP : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100

製品情報


由来:
Rabbit

精製方法:
Antigen affinity purification

アイソタイプ:
IgG

バッファー/保存方法:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.

ターゲット情報


正式名:
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

計算分子量:
78 kDa

検出分子量:
70-78 kDa

GenBank accession number:

Gene ID (NCBI):

遺伝子シンボル:
HSPA5

別名:
BIP, GRP 78, GRP78, HSP A5, HSPA5, MIF2
背景説明

GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).It is a constitutively expressed resident protein of the ER in all eukaryotic cells. Recently it has been reported that GRP78 is associated with apoptosis or inhibition of cancer cell growth. 11587-1-AP antibody recognizes one or two bands with MW 70-78 kDa for the signal peptide of GRP78 protein can be finally cleaved.


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