GRP94 抗体 8 文献

Rabbit Polyclonal| カタログ番号: 14700-1-AP

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43,900円

(希望販売価格)

容量: 36 μg/150 μl

Choose quantity:

販売および在庫状況はコスモ・バイオ(株)にお問い合わせください。
distributor

種特異性:
human, mouse, rat

WB ポジティブ:
HeLa cells, A549 cells, HEK-293 cells, HT-1080 cells, K-562 cells, MCF-7 cells, mouse heart tissue, mouse liver tissue, NIH/3T3 cells, rat liver tissue

IP ポジティブ:
mouse liver tissue

IHC ポジティブ:
human breast cancer tissue, human cervical cancer tissue

IF ポジティブ:
A431 cells, HepG2 cells

FC ポジティブ:
HEK-293T cells

推奨希釈倍率:
WB : 1:1000-1:4000
IP : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200

製品情報


由来:
Rabbit

精製方法:
Antigen affinity purification

アイソタイプ:
IgG

バッファー/保存方法:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.

ターゲット情報


正式名:
heat shock protein 90kDa beta (Grp94), member 1

計算分子量:
92 kDa

検出分子量:
100 kDa

GenBank accession number:

Gene ID (NCBI):

遺伝子シンボル:
HSP90B1

別名:
ECGP, Endoplasmin, GP96, gp96 homolog, GRP 94, GRP94, HSP90B1, TRA1, Tumor rejection antigen 1
背景説明

HSP90 proteins are highly conserved molecular chaperones, which normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 (GP96 or GRP94) is an endoplasmic reticulum paralogue of the cytosolic HSP90. As a major ER chaperone to mediate the UPR and a master chaperone for Toll-like receptors (TLRs), HSP90b1 chaperones peptides to MHC class I molecules of dendritic cells and other antigen-presenting cells, as well as facilitating the assembly of immunoglobulin. The protein is also involved in many other bio-processes. This antibody was generated against the C-terminal region of full-length HSP90b1.


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