HSP70 抗体 12 文献

Rabbit Polyclonal| カタログ番号: 10995-1-AP

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43,900円

(希望販売価格)

容量: 49 μg/150 μl

Choose quantity:

販売および在庫状況はコスモ・バイオ(株)にお問い合わせください。
distributor

種特異性:
human, mouse, rat, oysters

WB ポジティブ:
multi-cells/tissue, A431 cells, A549 cells, COLO 320 cells, HepG2 cells, human brain tissue, Jurkat cells, MCF-7 cells, mouse uterus tissue, PC-3 cells

IP ポジティブ:
mouse brain tissue

IHC ポジティブ:
human liver cancer tissue, human breast cancer tissue, human prostate cancer tissue

IF ポジティブ:
HepG2 cells

FC ポジティブ:
HepG2 cells

推奨希釈倍率:
WB : 1:1000-1:4000
IP : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:20-1:200

製品情報


由来:
Rabbit

精製方法:
Antigen affinity purification

アイソタイプ:
IgG

バッファー/保存方法:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.

ターゲット情報


正式名:
heat shock 70kDa protein 1A

計算分子量:
70 kDa

検出分子量:
66-70 kDa

GenBank accession number:

Gene ID (NCBI):

遺伝子シンボル:
HSPA1A

別名:
Heat shock 70 kDa protein 1/2, heat shock 70kDa protein 1A, HSP70, HSP70 1, HSP70 1/HSP70 2, HSP70 1A, HSP70.1/HSP70.2, HSP70I, HSP72, HSPA1, HSPA1A, HSPA1B
背景説明

HSPA1A , collectively known as HSP70 (also referred to HSP72), is a stress-inducible member of heat-shock protein 70 (HSP70) proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. Encoded by two closely linked, intronless and stress-inducible genes, HSPA1A and HSPA1B differ by only two amino acids and are believed to be fully interchangeable proteins. HSPA1A is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Generally, HSPA1A is thought to be expressed in unstressed normal cells at low or undetectable levels. Expression of HSPA1A protein can be highly activated by various stressful stimuli. Significant up-regulation of HSPA1A has been found in various tumors. Recently it has been reported that HSPA1A can be constitutively expressed in selected cell types. HSP70 is a useful marker for exosome. This antibody well recognized the endogenous HSP70 protein in multiple cell lines. (21373891)


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