ERp57/ERp60 抗体 14 文献

Rabbit Polyclonal| カタログ番号: 15967-1-AP

注目製品 KD/KO 検証済

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43,900円

(希望販売価格)

容量: 25 μg/150 μl

Choose quantity:

販売および在庫状況はコスモ・バイオ(株)にお問い合わせください。
distributor

種特異性:
human, mouse, rat, pig

WB ポジティブ:
L02 cells, A375 cells, mouse liver tissue, rat liver tissue

IP ポジティブ:
mouse liver tissue

IHC ポジティブ:
human lung cancer tissue

IF ポジティブ:
HepG2 cells

FC ポジティブ:
HepG2 cells

推奨希釈倍率:
WB : 1:500-1:2400
IP : 1:1000-1:4000
IHC : 1:20-1:200
IF : 1:20-1:200

製品情報


由来:
Rabbit

精製方法:
Antigen affinity purification

アイソタイプ:
IgG

バッファー/保存方法:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.

ターゲット情報


正式名:
protein disulfide isomerase family A, member 3

計算分子量:
505aa,57 kDa

検出分子量:
57 kDa

GenBank accession number:

Gene ID (NCBI):

遺伝子シンボル:
PDIA3

別名:
58 kDa microsomal protein, Disulfide isomerase ER 60, ER protein 57, ER protein 60, ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PDIA3, PI PLC, Protein disulfide isomerase A3
背景説明

PDIA3, also named as P58, ER60, ERp57, ERp60, ERp61, GRP57, GRP58 and PI-PLC, is a member of the PDI family, participates in the oxidation, reduction, and isomerization of disulfide bonds for correct folding of secretory proteins before modification and transport in the endoplasmic reticulum. It is associated with apoptosis or inhibition of cancer cell growth. PDIA3 was once thought to be a phospholipase; however, it has been demonstrated that this protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and PDIA3 mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.


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