TAP1 抗体 8 文献

Rabbit Polyclonal| カタログ番号: 11114-1-AP

注目製品 KD/KO 検証済

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43,900円

(希望販売価格)

容量: 36 μg/150 μl

Choose quantity:

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種特異性:
human, mouse, rat

WB ポジティブ:
HepG2 cells, human skeletal muscle tissue, mouse skeletal muscle tissue, mouse spleen tissue, Raji cells

IP ポジティブ:
HepG2 cells

IHC ポジティブ:
human pancreas cancer tissue, human lung cancer tissue

IF ポジティブ:
HepG2 cells

推奨希釈倍率:
WB : 1:500-1:2000
IP : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:20-1:200

製品情報


由来:
Rabbit

精製方法:
Antigen affinity purification

アイソタイプ:
IgG

バッファー/保存方法:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.

ターゲット情報


正式名:
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

計算分子量:
81 kDa

検出分子量:
70-81 kDa

GenBank accession number:

Gene ID (NCBI):

遺伝子シンボル:
TAP1

別名:
ABCB2, Antigen peptide transporter 1, PSF 1, RING 4, RING4, TAP1
背景説明

TAP1, also known as ABCB2, PSF1 or RING4, is a member of the ATP-binding cassette (ABC) family of transmembrane transporters and is an essential component of the major histocompatability complex (MHC) class I antigen-presenting pathway. TAP is involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It also acts as a molecular scaffold for the final stage of MHC class I folding. Defects in TAP1 are a cause of bare lymphocyte syndrome type 1 (BLS1). Western blot analysis using this antibody detected a major band around 70-80kD in HeLa cells.


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