CD31 (PECAM-1) Antibody

A Multi-Functional Molecule

A Multi-Functional Molecule
Antibody Catalog number Type Applications  
CD31 11265-1-AP Rabbit Poly ELISA, FC, IF, IHC, IP, WB 25 Publications

CD31 (PECAM-1 – platelet endothelial cell adhesion molecule-1) is an Ig gene superfamily member, composed of 6 extracellular Ig folds, with a molecular weight of 130 kDa. It is differentially glycosylated involving N-linked and O-linked glycosylation sites.

CD31 is expressed on all cells within the vascular compartment, on the surface of the endothelium. It plays a role in cell adhesion, being an efficient signaling molecule. This reflects the diverse roles of CD31 in vascular biology including angiogenesis, platelet function, thrombosis, mechanosensing of endothelial cell response to fluid shear stress, and regulation of multiple stages of leukocyte migration through venular walls.

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Posted:
20 September, 2017

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