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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

UBQLN4 Polyclonal antibody, PBS Only

UBQLN4 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 29413-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using UBQLN4 Polyclonal antibody (29413-1-AP)

    WB analysis using 29413-1-AP (same clone as 29413-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29413-1-AP (UBQLN4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29413-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using UBQLN4 Polyclonal antibody (29413-1-AP)

    IHC staining of human cervical cancer using 29413-1-AP (same clone as 29413-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 29413-1-AP (UBQLN4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29413-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using UBQLN4 Polyclonal antibody (29413-1-AP)

    IHC staining of human cervical cancer using 29413-1-AP (same clone as 29413-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 29413-1-AP (UBQLN4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29413-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using UBQLN4 Polyclonal antibody (29413-1-AP)

    IHC staining of human cervical cancer using 29413-1-AP (same clone as 29413-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 29413-1-AP (UBQLN4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29413-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

29413-1-PBS targets UBQLN4 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen UBQLN4 fusion protein Ag29658 相同性解析による交差性が予測される生物種
Full Name ubiquilin 4
Calculated molecular weight 601 aa, 64 kDa
Observed molecular weight70 kDa
GenBank accession numberBC063841
Gene symbol UBQLN4
Gene ID (NCBI) 56893
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Ubiquilins (UBQLNs) are important factors for cell proteostasis maintenance. UBQLNs are involved in the modulation of the cell cycle, as well as in apoptosis, membrane receptors regulation, DNA repair, epithelial-mesenchymal transition, and miRNA activities. Ubiquilin 4 (UBQLN4) is an important member of the ubiquitin-like protein family. UBQLN4 is overexpressed in aggressive tumors and inhibits homologous recombination, redirecting doublestrand break repair to nonhomologous end joining, resulting in increased genome instability and inducing carcinogenesis.