VCP 抗体 2 文献

Rabbit Polyclonal| カタログ番号: 10736-1-AP

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43,900円

(希望販売価格)

容量: 40 μg/150 μl

Choose quantity:

販売および在庫状況はコスモ・バイオ(株)にお問い合わせください。
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種特異性:
human, mouse, rat

WB ポジティブ:
SH-SY5Y cells, HeLa cells, human brain tissue, MCF-7 cells, mouse brain tissue, mouse lung tissue, mouse thymus tissue, rat brain tissue, rat lung tissue

IP ポジティブ:
HeLa cells

IHC ポジティブ:
human gliomas tissue, human colon cancer tissue, human lung cancer tissue

IF ポジティブ:
SH-SY5Y cells

推奨希釈倍率:
WB : 1:500-1:2000
IP : 1:500-1:2000
IHC : 1:100-1:400
IF : 1:10-1:100

製品情報


由来:
Rabbit

精製方法:
Antigen affinity purification

アイソタイプ:
IgG

バッファー/保存方法:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.

ターゲット情報


正式名:
valosin-containing protein

計算分子量:
89 kDa

検出分子量:
90-100 kDa

GenBank accession number:

Gene ID (NCBI):

遺伝子シンボル:
VCP

別名:
15S Mg(2+) ATPase p97 subunit, IBMPFD, p97, TER ATPase, TERA, valosin containing protein, VCP
背景説明

VCP(Valosin-containing protein), also known as TER ATPase and 15S Mg2+-ATPase p97 subunit, belongs to the AAA ATPase family. VCP was first identified as a result of attempts to clone a putative peptide hormone called valosin. It was found that the cloned cDNA encoded a ubiquitously expressed 90 kDa cytosolic protein, termed VCP, which showed none of the characteristics of a peptide hormone precursor(PMID:1382975). Defects in VCP are the cause of inclusion body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD) and amyotrophic lateral sclerosis type 14 with or without frontotemporal dementia (ALS14). VCP has a calculated molecular weight of 89 kDa and an apparent molecular weight of 90-100 kDa (PMID: 15732117, 1382975).


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