The ChromoTek Nano-Trap system provides fast, reliable, and effective immunoprecipitation of fusion proteins. More than 3,000 peer-reviewed articles have already been published using ChromoTek's Nano-Traps. The Nano-Traps consists of recombinant VHHs (Nanobodies) or Fab fragments coupled to beads.

Nano-Traps provides the following advantages:

• No heavy and light antibody chains 

• Very high affinity (K_D=1 pM  for GFP-Trap) 

• Effective, complete pulldown of fusion proteins.

• Allows for stringent washing

• Low background 

Available Nano-Trap targets: GFP, GST, Halo, MBP, MDM4, MK2, mNeonGreen, Myc, p53 C-term, p53 N-term, PARP1, RFP, SNAP/CLIP, SPOT, TurboGFP, V5, NEW DYKDDDDK Fab-Trap™ Agarose, and more!

Nano-Traps are available with up to three different beads:

• Agarose (for very low background and high binding capacity IP)

• Magnetic Agarose (for magnetic separation and high binding capacity IP) 

• Magnetic Particles M-270  (for IP of very large proteins/complexes) 

* Limit of 1 sample per customer