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IKBKB Polyclonal antibody

IKBKB Polyclonal Antibody for WB, IF, IHC, ELISA
Cat No. 20979-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

WB, IF, IHC, ELISA

I kappa B kinase 2, I kappa B kinase beta, IKBKB, IKK B, IKK beta, IKK2, IKKB, IκB, NFKBIKB

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inmouse testis tissue
Positive IHC detected inhuman breast cancer tissue, human pancreas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF/ICC detected inDU 145 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:100-1:400
Immunofluorescence (IF)/ICCIF/ICC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 5 publications below

Product Information

20979-1-AP targets IKBKB in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide 相同性解析による交差性が予測される生物種
Full Name inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Calculated molecular weight 87 kDa
Observed molecular weight 80 kDa, 86 kDa, 87 kDa
GenBank accession numberNM_001556
Gene Symbol IKBKB
Gene ID (NCBI) 3551
RRIDAB_2878780
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO14920
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

IKBKB, also named as NFKBIKB, IKK2 and IKKB, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and I-kappa-B kinase subfamily. IKBKB acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. It also phosphorylates NCOA3. The antibody is specific to IKBKB. This antibody can identify 3 isoform of IKBKB with the molecular weight of 80, 86, 87 kDa.

Protocols

Product Specific Protocols
WB protocol for IKBKB antibody 20979-1-APDownload protocol
IHC protocol for IKBKB antibody 20979-1-APDownload protocol
IF protocol for IKBKB antibody 20979-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Theranostics

Targeting BCL10 by small peptides for the treatment of B cell lymphoma.

Authors - Wei Bao
ratWB

Redox Biol

Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.

Authors - Dejuan Li
humanWB

Oncotarget

PMID: 26993770

Authors - Xueyuan Tang
ratWB

Inflammation

PMID: 28744711

Authors - Hongfei Zhao
mouseWB

Neurochem Res

Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1(G93A) ALS Mice.

Authors - Wan Wang
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