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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CoraLite®594-conjugated TMEM173/STING Recombinant antibody

TMEM173/STING Recombinant Antibody for IF-P

Host / Isotype

Rabbit / IgG

Reactivity

Human, Mouse, Rat

Applications

IF-P

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

7K7

Cat no : CL594-80165

Synonyms

FLJ38577, hMITA, hSTING, Mediator of IRF3 activation, MITA, MPYS, STING, TMEM173, transmembrane protein 173

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of human tonsillitis tissue using CoraLite®594-conjugated TMEM173/STING Recombinant (CL594-80165)

    IF Staining of human tonsillitis using CL594-80165

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®594 TMEM173/STING antibody (CL594-80165, Clone: 7K7 ) at dilution of 1:200.

  • Immunofluorescence (IF) / fluorescent staining of human tonsillitis tissue using CoraLite®594-conjugated TMEM173/STING Recombinant (CL594-80165)

    IF Staining of human tonsillitis using CL594-80165

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®594 TMEM173/STING antibody (CL594-80165, Clone: 7K7 ) at dilution of 1:200.

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Tested Applications

Positive IF-P detected inhuman tonsillitis tissue

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL594-80165 targets TMEM173/STING in IF-P applications and shows reactivity with Human, Mouse, Rat samples.

Tested Reactivity Human, Mouse, Rat
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen TMEM173/STING fusion protein Ag13921 相同性解析による交差性が予測される生物種
Full Name transmembrane protein 173
Calculated molecular weight 379 aa, 42 kDa
Observed molecular weight37 kDa
GenBank accession numberBC047779
Gene symbol STING
Gene ID (NCBI) 340061
RRIDAB_2920193
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths588 nm / 604 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Stimulator of interferon genes (STING, also known as ERIS, MITA and MPYS, and encoded by TMEM173) is a transmembrane adaptor protein that facilitates innate immune signaling (PMID: 18724357). STING is widely expressed in various cell types such as endothelial cells, epithelial cells, T cells, macrophages, and dendritic cells (PMID: 26603901). It is predominantly located in the endoplasmic reticulum (ER). STING functions as a sensor of cytosolic DNA and promotes the production of type I interferons and pro-inflammatory cytokines.

Protocols

Product Specific Protocols
IF protocol for CL594 TMEM173/STING antibody CL594-80165Download protocol
Standard Protocols
Click here to view our Standard Protocols