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Tested Applications
| Positive WB detected in | HEK-293 cells, HeLa cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
19764-1-AP targets ABCA13 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | ATP-binding cassette, sub-family A (ABC1), member 13 |
| Calculated molecular weight | 576 kDa |
| Observed molecular weight | 576 kDa |
| GenBank accession number | NM_152701 |
| Gene Symbol | ABCA13 |
| Gene ID (NCBI) | 154664 |
| RRID | AB_3669314 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q86UQ4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
ABCA13 belongs to the ABC transporter superfamily. ABCA13 is a transmembrane protein with the typical structure of ABC proteins: two transmembrane domains and two nucleotide-binding domains. ABCA13 may mediate the cholesterol and gangliosides transport from the plasma membrane to intracellular vesicles in an ATP hydrolysis-dependent manner, thus playing a role in their internalization by endocytic retrograde transport (PMID: 33478937). ABCA13 is expressed in the human trachea, testis, and bone marrow(PMID:12697998).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for ABCA13 antibody 19764-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |