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Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
26834-1-PBS targets ACMSD in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | ACMSD fusion protein Ag25230 相同性解析による交差性が予測される生物種 |
| Full Name | aminocarboxymuconate semialdehyde decarboxylase |
| Calculated molecular weight | 38 kDa |
| GenBank accession number | BC016018 |
| Gene Symbol | ACMSD |
| Gene ID (NCBI) | 130013 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8TDX5 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
ACMSD (alpha-amino-beta-carboxy-muconate-semialdehyde decarboxylase ) is the key enzyme that regulates the de novo NAD+ synthesis from tryptophan. ACMSD is highly expressed in the liver, kidney and to a lower degree in brain under physiological conditions. The enzyme is primarily cytosolic and is positioned at a critical branching point in the kynurenine pathway, wherein it influences the fate of the precursor 2-amino-3-carboxymuconic-6-semialdehyde (ACMS).