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- KD/KO Validated
ACSL4/FACL4 Recombinant antibody, PBS Only
ACSL4/FACL4 Recombinant Antibody for WB, IHC, IP, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IHC, IP, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3I9
Cat no : 81196-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
81196-1-PBS targets ACSL4/FACL4 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | ACSL4/FACL4 fusion protein Ag18085 相同性解析による交差性が予測される生物種 |
Full Name | acyl-CoA synthetase long-chain family member 4 |
Calculated molecular weight | 711 aa, 79 kDa |
Observed molecular weight | 70 kDa, 75 kDa |
GenBank accession number | BC034959 |
Gene symbol | ACSL4 |
Gene ID (NCBI) | 2182 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Acyl-CoA synthetase long-chain family member 4 (Acsl4), an important enzyme involved in lipid metabolism, participates in ferroptosis by converting free AA into arachidonoyl-CoA to generate lipid hydroperoxides. Recent studies revealed that ACSL4 is involved in biological responses including inflammation, steroidogenesis, cell death, female fertility, and cancer. Acsl4 has two isoforms: 79 kDa and 75 kDa. ACSL4 also can be detected in 70 kDa(PMID:35326233).