• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
×

Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

ACVRL1 Polyclonal antibody, PBS Only

ACVRL1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 14745-1-PBS

Synonyms

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of human placenta tissue using ACVRL1 Polyclonal antibody (14745-1-AP)

    WB analysis of human placenta using 14745-1-AP (same clone as 14745-1-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 14745-1-AP (ACVRL1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14745-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human placenta tissue using ACVRL1 Polyclonal antibody (14745-1-AP)

    WB analysis of human placenta using 14745-1-AP (same clone as 14745-1-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 14745-1-AP (ACVRL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14745-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of Jurkat cells using ACVRL1 Polyclonal antibody (14745-1-AP)

    IP experiment of Jurkat using 14745-1-AP (same clone as 14745-1-PBS)

    IP result of anti-ACVRL1 (IP:14745-1-AP, 4ug; Detection:14745-1-AP 1:300) with Jurkat cells lysate 2400ug. This data was developed using the same antibody clone with 14745-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human heart tissue using ACVRL1 Polyclonal antibody (14745-1-AP)

    IHC staining of human heart using 14745-1-AP (same clone as 14745-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 14745-1-AP (ACVRL1 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 14745-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lymphoma tissue using ACVRL1 Polyclonal antibody (14745-1-AP)

    IHC staining of human lymphoma using 14745-1-AP (same clone as 14745-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma using 14745-1-AP (ACVRL1 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 14745-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lymphoma tissue using ACVRL1 Polyclonal antibody (14745-1-AP)

    IHC staining of human lymphoma using 14745-1-AP (same clone as 14745-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma using 14745-1-AP (ACVRL1 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 14745-1-PBS in a different storage buffer formulation.

☆対象製品が30%オフ！組換えタンパク質&免染用試薬 >>> キャンペーン実施中！

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

14745-1-PBS targets ACVRL1 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ACVRL1 fusion protein Ag6449 相同性解析による交差性が予測される生物種
Full Name activin A receptor type II-like 1
Calculated molecular weight 56 kDa
Observed molecular weight 63 kDa
GenBank accession numberBC042637
Gene symbol ACVRL1
Gene ID (NCBI) 94
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ACVRL1 (also known as ALK1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1 is highly expressed in endothelial cells and has a critical role in the control of blood vessel development and repair (PMID: 8640225). Mutations in the ACVRL1 gene are associated with hemorrhagic telangiectasia type 2.