ADCY6 Polyclonal antibody

ADCY6 Polyclonal Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, ELISA

Conjugate

Unconjugated

Cat no : 14616-1-AP

Synonyms

AC6, ADCY6, adenylate cyclase 6, Adenylate cyclase type 6, Adenylate cyclase type VI, Adenylyl cyclase 6, ATP pyrophosphate lyase 6, KIAA0422


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Tested Applications

Positive WB detected inhuman brain tissue, mouse brain tissue
Positive IP detected inmouse brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14616-1-AP targets ADCY6 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ADCY6 fusion protein Ag6218 相同性解析による交差性が予測される生物種
Full Name adenylate cyclase 6
Calculated molecular weight 131 kDa
Observed molecular weight 131 kDa
GenBank accession numberBC064923
Gene symbol ADCY6
Gene ID (NCBI) 112
RRIDAB_2242343
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
WB protocol for ADCY6 antibody 14616-1-APDownload protocol
IP protocol for ADCY6 antibody 14616-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Nat Commun

Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH)

Authors - Xinzhi Li
mouseWB

J Cell Biol

Sonic Hedgehog activates prostaglandin signaling to stabilize primary cilium length

Authors - Shariq S Ansari
mouseWB

Mol Metab

Purβ promotes hepatic glucose production by increasing Adcy6 transcription.

Authors - Linna Jia
humanWB

Mol Pharmacol

Activity of adenylyl cyclase type 6 is suppressed by direct binding of the cytoskeletal protein 4.1G.

Authors - Masaki Saito
humanWB

Pathol Oncol Res

Knockdown of GPSM1 Inhibits the Proliferation and Promotes the Apoptosis of B-Cell Acute Lymphoblastic Leukemia Cells by Suppressing the ADCY6-RAPGEF3-JNK Signaling Pathway.

Authors - Ye Zhang
humanWB

Eur J Pharmacol

Forskolin is an effective therapeutic small molecule for the treatment of hypertrophic cardiomyopathy through ADCY6/cAMP/PKA pathway

Authors - Wenyan Wang
  • KD Validated

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Charlotte (Verified Customer) (07-27-2022)

1 and 2 : WT starved and ShhN stimulated. 3 to 6 are ADC6 KO cells with 2 different gRNAs. 3/4 is one gRNA and 5/6 is another one. 3 and 5 are starved while 4 and 6 are ShhN stimulated

  • Applications: Western Blot
  • Primary Antibody Dilution: 1/500
  • Cell Tissue Type: NIH-3T3
ADCY6 Antibody Western Blot validation (1/500 dilution) in NIH-3T3 (Cat no:14616-1-AP)