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  • KD/KO Validated

ADCY8 Polyclonal antibody

ADCY8 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 55065-1-AP

Synonyms

AC8, ADCY3, ADCY8, adenylate cyclase 8 (brain), Adenylate cyclase type 8, Adenylate cyclase type VIII, Adenylyl cyclase 8, ATP pyrophosphate lyase 8, HBAC1


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Tested Applications

Positive WB detected inNeuro-2a cells, SH-SY5Y cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

55065-1-AP targets ADCY8 in WB, IF, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide 相同性解析による交差性が予測される生物種
Full Name adenylate cyclase 8 (brain)
Calculated molecular weight 140 kDa
Observed molecular weight 140-150 kDa
GenBank accession numberNM_001115
Gene symbol ADCY8
Gene ID (NCBI) 114
RRIDAB_10859258
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

ADCY8 Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence. The antibody is specific to ADCY8.

Protocols

Product Specific Protocols
WB protocol for ADCY8 antibody 55065-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIF

Phytochemistry

Hypoglycemic flavonoids from Selaginella tamariscina (P.Beauv.) Spring.

Authors - Hong-Ping Long
humanWB

Function (Oxf)

AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca2+ Channels.

Authors - Pulak Kar
humanWB

Nat Commun

A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction.

Authors - Xuexin Zhang
  • KD Validated
ratWB,IF

Mol Ther

Inhibition of adenylyl cyclase 8 prevents the upregulation of Orai1 channel which improves cardiac function after myocardial infarction

Authors - Débora Falcón
WB

Int J Mol Sci

Combined Proteomic and Metabolomic Analysis Reveals Comprehensive Regulation of Somatostatin DNA Vaccine in Goats

Authors - Ge Qin