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- KD/KO Validated
ADCY8 Polyclonal antibody
ADCY8 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse and More (1)
Applications
WB, IF, ELISA
Conjugate
Unconjugated
Cat no : 55065-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | Neuro-2a cells, SH-SY5Y cells |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Published Applications
KD/KO | See 1 publications below |
WB | See 4 publications below |
IF | See 2 publications below |
Product Information
55065-1-AP targets ADCY8 in WB, IF, ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Cited Reactivity | human, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
Full Name | adenylate cyclase 8 (brain) |
Calculated molecular weight | 140 kDa |
Observed molecular weight | 140-150 kDa |
GenBank accession number | NM_001115 |
Gene symbol | ADCY8 |
Gene ID (NCBI) | 114 |
RRID | AB_10859258 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
Background Information
ADCY8 Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence. The antibody is specific to ADCY8.
Protocols
Product Specific Protocols | |
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WB protocol for ADCY8 antibody 55065-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Function (Oxf) AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca2+ Channels. | ||
Nat Commun A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction.
| ||
Mol Ther Inhibition of adenylyl cyclase 8 prevents the upregulation of Orai1 channel which improves cardiac function after myocardial infarction | ||
Int J Mol Sci Combined Proteomic and Metabolomic Analysis Reveals Comprehensive Regulation of Somatostatin DNA Vaccine in Goats |