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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
84546-1-PBS targets ADH1C in WB, Indirect ELISA applications and shows reactivity with mouse samples.
| Tested Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | ADH1C fusion protein Ag13528 相同性解析による交差性が予測される生物種 |
| Full Name | alcohol dehydrogenase 1C (class I), gamma polypeptide |
| Calculated molecular weight | 375 aa, 40 kDa |
| Observed molecular weight | 40 kDa |
| GenBank accession number | BC062476 |
| Gene Symbol | ADH1C |
| Gene ID (NCBI) | 126 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | P00326 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
Alcohol dehydrogenase 1C(ADH1C), also known as ADH3, is an alcohol dehydrogenase that can catalyze ethanol oxidation to metabolite acetaldehyde. According to THE HUMAN PROTEIN ATLAS database, ADH1C locates mainly to the cytosol and plasma membrane. Genetic polymorphism of the ADH1C gene (ADH1C*1 allele) is associated with various human cancers, such as gastric cancer, oral cancer and CRC, for it encodes an alcohol dehydrogenase producing 2.5 times more acetaldehyde.(PMID: 35300114)