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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

AGXT2L1 Polyclonal antibody, PBS Only

AGXT2L1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17042-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using AGXT2L1 Polyclonal antibody (17042-1-AP)

    WB analysis using 17042-1-AP (same clone as 17042-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17042-1-AP (AGXT2L1 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17042-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse liver tissue using AGXT2L1 Polyclonal antibody (17042-1-AP)

    IHC staining of mouse liver using 17042-1-AP (same clone as 17042-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 17042-1-AP (AGXT2L1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17042-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using AGXT2L1 Polyclonal antibody (17042-1-AP)

    IHC staining of mouse brain using 17042-1-AP (same clone as 17042-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 17042-1-AP (AGXT2L1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17042-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using AGXT2L1 Polyclonal antibody (17042-1-AP)

    IHC staining of mouse brain using 17042-1-AP (same clone as 17042-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 17042-1-AP (AGXT2L1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17042-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

17042-1-PBS targets AGXT2L1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen AGXT2L1 fusion protein Ag10584 相同性解析による交差性が予測される生物種
Full Name alanine-glyoxylate aminotransferase 2-like 1
Calculated molecular weight 499 aa, 56 kDa
Observed molecular weight50-55 kDa
GenBank accession numberBC022526
Gene symbol AGXT2L1
Gene ID (NCBI) 64850
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Alanine-glyoxylate aminotransferase 2-like 1 (AGXT2L1), also called ethanolamine phosphate phospholyase (ETNPPL), is a brain enzyme, so-named after its similarity to AGXT2 (36% sequence identity), that may be involved in the pathogenesis of severe neuropsychiatric disturbances(PMID: 23761375). AGXT2L1 is significantly down-regulated in cancerous tissues and may be a tumor suppressor(PMID: 26294768, 32724374).