- Featured Product
- KD/KO Validated
ALDH2 Monoclonal antibody, PBS Only
ALDH2 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human, Mouse, Rat, Rabbit, Pig
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2G10F4
Cat no : 68237-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
68237-1-PBS targets ALDH2 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat, Rabbit, Pig samples.
Tested Reactivity | Human, Mouse, Rat, Rabbit, Pig |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | ALDH2 fusion protein Ag7463 相同性解析による交差性が予測される生物種 |
Full Name | aldehyde dehydrogenase 2 family (mitochondrial) |
Calculated molecular weight | 56 kDa |
Observed molecular weight | 50-55 kDa |
GenBank accession number | BC002967 |
Gene symbol | ALDH2 |
Gene ID (NCBI) | 217 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Acetaldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. It mediates NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. Genetic variation in ALDH2 is responsible for individual differences in responses to drinking alcohol. Thus, the absence of this enzyme is linked to alcohol intolerance and a reduced risk for alcoholism-related liver disease.