Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
83912-5-PBS targets ANK2 in IF-P, FC (Intra), ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | ANK2 fusion protein Ag34642 相同性解析による交差性が予測される生物種 |
Full Name | ankyrin 2, neuronal |
Calculated molecular weight | 434 kDa |
Observed molecular weight | 250-260 kDa |
GenBank accession number | NM_001148 |
Gene Symbol | ANK2 |
Gene ID (NCBI) | 287 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q01484 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
The Ankyrins, belonging to the adapter protein family, consist of Ankyrin-R (ANK1), Ankyrin-B (ANK2), and Ankyrin-G (ANK3). Initially, ANK2 was considered as a key cytoskeletal-associated protein in the brain. Besides, it was discovered as a pivotal adaptor and scaffolding protein in the heart. Remarkably, recent studies have demonstrated that Ankyrins contribute to the modulation of various biological activities in cancers. (PMID: 36539782)