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ANLN Monoclonal antibody, PBS Only

ANLN Monoclonal Antibody for WB, IF/ICC, ELISA
Cat No. 66643-1-PBS
Clone No.1B4A8

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IF/ICC, ELISA

Anillin, Scraps, scra, anillin, actin binding protein, Actin binding protein anillin

Formulation:  PBS Only
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

66643-1-PBS targets ANLN in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen ANLN fusion protein Ag19294 相同性解析による交差性が予測される生物種
Full Name anillin, actin binding protein
Calculated molecular weight 1124 aa, 124 kDa
Observed molecular weight 110 kDa~120 kDa
GenBank accession numberBC034692
Gene Symbol ANLN
Gene ID (NCBI) 54443
RRIDAB_2815000
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ9NQW6
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

Anillin, an actin-binding protein, is a conserved cleavage furrow component important for cytokinesis. The human anillin protein localizes to the nucleus during interphase, the cortex following nuclear envelope breakdown, and the cleavage furrow during cytokinesis. It interactions with at least two other furrow proteins, actin and the septins through its C-terminal PH domain and N-terminal actin-binding domain. In anillin knockdown cells, the cleavage furrow ingressed but failed to complete the ingression. Anillin has been found to be overexpressed in tumors and may serve as promising marker for pancreatic carcinoma molecular diagnostics as well as a prognostic indicator for non-small cell lung cancers.

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