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ANP32B Monoclonal antibody, PBS Only
ANP32B Monoclonal Antibody for WB, IF, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human, mouse, rat
Applications
WB, IF, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
5A1F12
Cat no : 66160-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66160-1-PBS targets ANP32B in WB, IF, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | ANP32B fusion protein Ag1274 相同性解析による交差性が予測される生物種 |
Full Name | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B |
Calculated molecular weight | 29 kDa |
Observed molecular weight | 29 kDa |
GenBank accession number | BC013003 |
Gene symbol | ANP32B |
Gene ID (NCBI) | 10541 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
ANP32B is a member of the highly conserved acidic leucine-rich nuclear phosphoprotein 32 (ANP32) family. The ANP32 proteins have been implicated in a broad array of physiological processes, including cell differentiation, apoptotic cell death, and cell proliferation. ANP32B was identified as a novel direct substrate for caspase-3 and acted as a negative regulator for leukemic cell apoptosis. ANP32B controls the expression of the dendritic cell maturation factor CD83 by regulating the transport of its mRNA to the cytoplasm. It also modulates the activity of the transcription factor Kruppel-like factor 5 (KLF5).