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APOL1 Recombinant antibody, PBS Only

APOL1 Uni-rAbTM Recombinant Antibody for WB, IF/ICC, ELISA
Cat No. 83770-5-PBS
Clone No.240814D11

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, ELISA

Apolipoprotein L-I, Apolipoprotein L I, ApoL-I, Apo-L, 240814D11

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

83770-5-PBS targets APOL1 in WB, IF/ICC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen APOL1 fusion protein ag2016 相同性解析による交差性が予測される生物種
Full Name apolipoprotein L, 1
Calculated molecular weight 44 kDa
Observed molecular weight 39 kDa
GenBank accession numberBC017331
Gene Symbol APOL1
Gene ID (NCBI) 8542
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO14791
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Human apolipo-protein L1 (APOL1) is a minor component of plasma high density lipoprotein (HDL) particles, acting as an interacting protein of apolipoprotein A1 (ApoA1). The human ApoL protein family was thought to be predominantly involved in lipid transport and metabolism. APOL1 is also involved in host innate immunity against Trypanosoma parasites. Once activated, APOL1 can lyse the parasite and protect human from infection. Genetic variants in APOL1 gene, which are found in African ancestry with high frequency, associate with chronic kidney disease, like focal segmental glomerulosclerosis (FSGS), HIV-associated nephropathy (HIVAN), and hypertensive nephropathy. APOL1 share structural and functional similarities with proteins of the Bcl-2 family and may has roles in apoptosis and autophagy. It is notable that APOL1 exists only in human and a few other primate species, and mouse does not express an APOL1 orthologue.

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