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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

ARAP3 Polyclonal antibody, PBS Only

ARAP3 Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 22578-1-PBS

Synonyms

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human colon tissue using ARAP3 Polyclonal antibody (22578-1-AP)

    IHC staining of human colon using 22578-1-AP (same clone as 22578-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon cancer tissue using ARAP3 Polyclonal antibody (22578-1-AP)

    IHC staining of human colon cancer using 22578-1-AP (same clone as 22578-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon tissue using ARAP3 Polyclonal antibody (22578-1-AP)

    IHC staining of human colon using 22578-1-AP (same clone as 22578-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon cancer tissue using ARAP3 Polyclonal antibody (22578-1-AP)

    IHC staining of human colon cancer using 22578-1-AP (same clone as 22578-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

22578-1-PBS targets ARAP3 in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ARAP3 fusion protein Ag17436 相同性解析による交差性が予測される生物種
Full Name ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Calculated molecular weight 1544 aa, 170 kDa
GenBank accession numberBC009968
Gene symbol ARAP3
Gene ID (NCBI) 64411
RRIDAB_2879125
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. These proteins are best characterized as regulators of membrane traffic. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. ARAP3 (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3) is unique for its dual specificity GAPs (GTPase activating protein) activity for Arf6 (ADP-ribosylation factor 6) and RhoA (Ras homolog gene family member A) regulated by PtdIns(3,4,5)P3 (phosphatidylinositol (3,4,5)-trisphosphate) and a small GTPase Rap1-GTP and is involved in regulation of cell shape and adhesion.