ASF/SF2 Monoclonal antibody, PBS Only
ASF/SF2 Monoclonal Antibody for WB, IP, IF, IHC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat
Applications
WB, IP, IF, IHC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1A6C5
Cat no : 66671-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66671-1-PBS targets ASF/SF2 in WB, IP, IF, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | ASF/SF2 fusion protein Ag3626 相同性解析による交差性が予測される生物種 |
Full Name | splicing factor, arginine/serine-rich 1 |
Calculated molecular weight | 248 aa, 28 kDa |
Observed molecular weight | 32 kDa, 28 kDa, 22 kDa |
GenBank accession number | BC010264 |
Gene symbol | ASF/SF2 |
Gene ID (NCBI) | 6426 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
SFRS1, also named as ASF, SF2, SF2P33, SFRS1 and ASF-1, belongs to the splicing factor SR family. It plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. SFRS1 interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Isoform ASF-2 and isoform ASF-3 act as splicing repressors. This antibody can recognize all the 3 isoforms(28kd,33kd and 22kd) of SFRS1.