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- KD/KO Validated
ATG7 Monoclonal antibody, PBS Only
ATG7 Monoclonal Antibody for WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
pig, rat, mouse, human
Applications
WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2B5A10
Cat no : 67341-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
67341-1-PBS targets ATG7 in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with pig, rat, mouse, human samples.
Tested Reactivity | pig, rat, mouse, human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | ATG7 fusion protein Ag29172 相同性解析による交差性が予測される生物種 |
Full Name | ATG7 autophagy related 7 homolog (S. cerevisiae) |
Calculated molecular weight | 78 kDa |
Observed molecular weight | 68-78 kDa |
GenBank accession number | BC000091 |
Gene symbol | ATG7 |
Gene ID (NCBI) | 10533 |
RRID | AB_2882599 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Atg7 is an E1-like enzyme that is specifically involved in autophagosome formation and is essential for autophagy. As an autophagic-related protein it is required for linking to Atg12, Atg5 and Atg8, which are essential for Atg conjugation and autophagosome formation. Atg7 has been reported as an important regulator of autophagy with starvation-induced or chemotherapeutic agent treatment. The high expression level of ATG7 is related to the survival of patients with breast cancer. There are several isoforms of ATG7 protein ranged from 68 kDa to 78 kDa.