Alpha Antichymotrypsin Monoclonal antibody, PBS Only
Alpha Antichymotrypsin Monoclonal Antibody for WB, IF, IHC, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human, pig
Applications
WB, IF, IHC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3F2F10
Cat no : 66078-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66078-1-PBS targets Alpha Antichymotrypsin in WB, IF, IHC, Indirect ELISA applications and shows reactivity with human, pig samples.
Tested Reactivity | human, pig |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | Alpha Antichymotrypsin fusion protein Ag2830 相同性解析による交差性が予測される生物種 |
Full Name | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
Calculated molecular weight | 448 aa, 48 kDa |
Observed molecular weight | 60 kDa |
GenBank accession number | BC010530 |
Gene symbol | Alpha 1 Antichymotrypsin |
Gene ID (NCBI) | 12 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Human SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease (COPD), Parkinson's disease (PD), Alzheimer's disease (AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.