Anti-Mouse B7-H3/CD276 (MJ18), PBS Only

B7-H3/CD276 Monoclonal Antibody for FC

Host / Isotype

Rat / IgG1, kappa

Reactivity

mouse

Applications

FC

Conjugate

Unconjugated

CloneNo.

MJ18

Cat no : 65221-1-PBS

Synonyms

Cd276, CD276 antigen, B7RP 2, B7-H3, B7h3


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Tested Applications

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

65221-1-PBS targets B7-H3/CD276 in FC applications and shows reactivity with mouse samples.

Tested Reactivity mouse
Host / Isotype Rat / IgG1, kappa
Class Monoclonal
Type Antibody
Immunogen Mouse IgG2a Fc-CD276 (aa 1-242) fusion protein 相同性解析による交差性が予測される生物種
Full Name CD276 antigen
GenBank accession numberBC019436
Gene symbol Cd276
Gene ID (NCBI) 102657
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CD276 (also known as B7-H3) is a type I transmembrane protein expressed on many tissues and cell types. CD276 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, CD276 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).