BBS4 Recombinant antibody
BBS4 Recombinant Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
ELISA
Conjugate
Unconjugated
CloneNo.
230303E4
Cat no : 82961-3-RR
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
82961-3-RR targets BBS4 in ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | BBS4 fusion protein Ag3430 相同性解析による交差性が予測される生物種 |
Full Name | Bardet-Biedl syndrome 4 |
Calculated molecular weight | 519 aa, 58 kDa |
GenBank accession number | BC027624 |
Gene symbol | BBS4 |
Gene ID (NCBI) | 585 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
BBS4 (Bardet-Biedl syndrome protein 4) is one of the early BBS proteins discovered, with 35 mutations reported to cause the BBS phenotype (PMID: 26762677). BBS4 undergoes localization to the centriolar satellites of centrosomes and basal body of primary cilia, where it takes part in recruiting cargo to centriolar satellites and allowing the formation of a functional centrosomal microtubule organizing center (MTOC) (PMID: 25860617). Some research has found that BBS4 expression in humans during the development of CNS and sensory organs, concerning the cardinal clinical signs of BBS (PMID: 33860840).