BCAM Polyclonal antibody
BCAM Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 26528-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | A431 cells, HT-29 cells, human placenta tissue |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:2000-1:16000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
26528-1-AP targets BCAM in WB, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | BCAM fusion protein Ag24753 相同性解析による交差性が予測される生物種 |
Full Name | basal cell adhesion molecule (Lutheran blood group) |
Calculated molecular weight | 67 kDa |
Observed molecular weight | 78 kDa, 85 kDa |
GenBank accession number | BC050450 |
Gene symbol | BCAM |
Gene ID (NCBI) | 4059 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Basal cell adhesion molecule (Lu/BCAM) is a 90 kDa membrane-bound glycoprotein of the immunoglobulin superfamily (IgSF), functioning as a receptor for the extracellular matrix protein, laminin. BCAM, involved in cell adhesion and migration, can also promote tumor metastasis and has been elucidated to play a functional role in the metastasis of thyroid cancer and gastric cancer (PMID: 35941663). Two Lu/BCAM glycoprotein (gp) isoforms are present on human RBCs, Lu (85 kDa) and Lu(v13) (78 kDa); they result from the alternative splicing of intron 13 and differ by the lengths of their cytoplasmic domains (PMID: 23160466)..
Protocols
Product Specific Protocols | |
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WB protocol for BCAM antibody 26528-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |