Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
19790-1-AP targets BCR-Specific in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | breakpoint cluster region |
| Calculated molecular weight | 143 kDa |
| GenBank accession number | NM_004327 |
| Gene Symbol | BCR |
| Gene ID (NCBI) | 613 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P11274 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
BCR, also named as BCR1 and D22S11, is a GTPase-activating protein for RAC1 and CDC42. BCR promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. BCR displays serine/threonine kinase activity. BCR catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein. A chromosomal aberration involving BCR is a cause of chronic myeloid leukemia (CML). The antibody is specific to BCR.