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BUB1 Polyclonal antibody, PBS Only

BUB1 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 13330-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, canine

Applications

WB, IF/ICC, Indirect ELISA

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

13330-1-PBS targets BUB1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, canine samples.

Tested Reactivity human, canine
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen BUB1 fusion protein Ag4138 相同性解析による交差性が予測される生物種
Full Name budding uninhibited by benzimidazoles 1 homolog (yeast)
Calculated molecular weight 1085 aa, 122 kDa
Observed molecular weight 45 kDa, 120 kDa
GenBank accession numberBC028201
Gene Symbol BUB1
Gene ID (NCBI) 699
RRIDAB_2814999
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO43683
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Bub1 is an evolutionarily conserved mitotic checkpoint control protein that is present in diverse organisms including yeast and humans. Bub1 is a serine/threonine protein kinase and is required for recruitment of Mad1, Mad2, Bub3, and CENP-E to kinetochores. Full-length Bub1 protein was cleaved to an 45 kDa fragment and an intermediate fragment of 90 kDa, only detected at early stages of apoptosis execution, indicating cleavage of Bub1 in the amino- and carboxy-terminal regions of the protein(PMID:15818396).

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