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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

C11orf82 Polyclonal antibody

C11orf82 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 27754-1-AP

Synonyms

noxin, Nitric oxide-inducible gene protein, DNA damage-induced apoptosis suppressor protein, DNA Damage Induced Apoptosis Suppressor, DDIAS

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using C11orf82 Polyclonal antibody (27754-1-AP)

    WB analysis using 27754-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 27754-1-AP (C11orf82 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Tested Applications

Positive WB detected inHepG2 cells, K-562 cells, NCI-H1299 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

27754-1-AP targets C11orf82 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen C11orf82 fusion protein Ag26829 相同性解析による交差性が予測される生物種
Full Name chromosome 11 open reading frame 82
Observed molecular weight120 kDa
GenBank accession numberBC039268
Gene symbol C11orf82
Gene ID (NCBI) 220042
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

DNA damage-induced apoptosis suppressor (DDIAS) is an oncogenic protein that is highly expressed in several cancers, including colorectal, lung, breast, and hepatocellular carcinoma (HCC), and stimulates cancer cell proliferation and cell cycle progression.DDIAS protects cancer cells from DNA damage reagents and tumor necrosis factor-associated apoptosis-inducing ligands (TRAILs) and positively regulates cancer cell invasion by stabilizing the β- catenin positively regulates cancer cell invasion. Therefore, DDIAS is considered as a potential therapeutic target for malignant lung cancer.

Protocols

Product Specific Protocols
WB protocol for C11orf82 antibody 27754-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols