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Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
26131-1-PBS targets C6orf25 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | C6orf25 fusion protein Ag23442 相同性解析による交差性が予測される生物種 |
| Full Name | chromosome 6 open reading frame 25 |
| Observed molecular weight | 24-29 kDa |
| GenBank accession number | BC113719 |
| Gene Symbol | C6orf25 |
| Gene ID (NCBI) | 80739 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O95866 |
| Storage Buffer | PBS only , pH 7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
C6orf25, also called G6B, is an inhibitory receptor expressed on the surface of platelets,and it acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production (PMID: 17311996; 12665801; 27743390). C6orf25 has seven isoforms. Isoform B is the only isoform to contain both a transmembrane region and 2 immunoreceptor tyrosine-based inhibitor motifs (ITIMs) and, thus, the only one which probably has a role of inhibitory receptor. Isoform A may be the activating counterpart of isoform B (PMID: 11544253).