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CC2D1A Monoclonal antibody, PBS Only

CC2D1A Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 68334-1-PBS
Clone No.1C11G2

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

CC2D1A, FLJ20241, FLJ41160, FREUD 1, Freud 1/Aki1, MRT3

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

68334-1-PBS targets CC2D1A in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.

Tested Reactivity Human, Mouse, Rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen CC2D1A fusion protein Ag10363 相同性解析による交差性が予測される生物種
Full Name coiled-coil and C2 domain containing 1A
Calculated molecular weight 951 aa, 104 kDa
Observed molecular weight 130 kDa
GenBank accession numberBC064981
Gene Symbol CC2D1A
Gene ID (NCBI) 54862
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ6P1N0
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CC2D1A (coiled-coil and C2 domain-containing 1A), also known as Freud-1, Aki1 or TAPE (TBK1-associated protein in endolysosomes), is a evolutionary conserved protein located in different subcellular compartments, including the nucleus, centrosome, and endolysosomes. It acts as a scaffold protein that interacts with various proteins and plays diverse biological roles. Mutations in CC2D1A have been linked to nonsyndromic mental retardation (NMSR) and generate a truncated 85-kDa product. Several isoforms of CC2D1A proteins have also been described: 120 /130-kDa doublet of long isoform and 67 kDa short isoform. The short isoform of CC2D1A has been identified as the predominant isoform in rodent cells, while the long isoform is more abundant in human cells. Recently it has been reported that CC2D1A/TAPE is the first innate immune regulator implicated in both TLR and RLR signaling at a very early step.

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