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CCAR1 Recombinant antibody, PBS Only

CCAR1 Uni-rAbTM Recombinant Antibody for WB, IF/ICC, ELISA
Cat No. 83936-4-PBS
Clone No.240980C12

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, ELISA

DIS, Death inducer with SAP domain, CARP-1, CARP1, CARP 1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

83936-4-PBS targets CCAR1 in WB, IF/ICC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen CCAR1 fusion protein Ag18786 相同性解析による交差性が予測される生物種
Full Name cell division cycle and apoptosis regulator 1
Calculated molecular weight 1150 aa, 133 kDa
Observed molecular weight150 kDa
GenBank accession numberBC132725
Gene Symbol CCAR1
Gene ID (NCBI) 55749
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ8IX12
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Cell cycle and apoptosis regulator 1 (CCAR1) was originally identified from a functional screening and implicated in retinoid-induced cell cycle arrest and apoptosis. It has been shown that, in breast cancer cells, CCAR1 regulates apoptosis induced by various agents, including chemotherapeutics adriamycin, etoposide, and EGFR inhibitor. It is also involved in mediating anchorage-independent growth of colon carcinoma cells. In addition, CCAR1 plays the role as a co-activator of nuclear receptors to recruit mediator complex. It was found to associate with components of the Mediator and p160 coactivator complexes and is recruited to endogenous NR target genes. CCAR1 is also a binding partner of b-catenin and assists b-catenin in transcriptional activation of Wnt target genes.

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