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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CCBE1 Polyclonal antibody, PBS Only

CCBE1 Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 24449-1-PBS

Synonyms

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human kidney tissue using CCBE1 Polyclonal antibody (24449-1-AP)

    IHC staining of human kidney using 24449-1-AP (same clone as 24449-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 24449-1-AP (CCBE1 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 24449-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human kidney tissue using CCBE1 Polyclonal antibody (24449-1-AP)

    IHC staining of human kidney using 24449-1-AP (same clone as 24449-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 24449-1-AP (CCBE1 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 24449-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

24449-1-PBS targets CCBE1 in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CCBE1 fusion protein Ag19686 相同性解析による交差性が予測される生物種
Full Name collagen and calcium binding EGF domains 1
Calculated molecular weight 406 aa, 44 kDa
GenBank accession numberBC046645
Gene symbol CCBE1
Gene ID (NCBI) 147372
RRIDAB_2879553
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CCBE1 (collagen and calcium-binding EGF domain-containing protein 1) is a secreted protein that is indispensible for lymphangiogenesis during development. CCBE1 may be a guidance molecule that regulates lymphangioblast budding and possibly migration (PMID: 19287381). The gene of CCBE1 maps to 18q21.32 and encodes a protein of 44 kDa that contains an EGF-like domain and two collagen-like domains. Mutations in the CCBE1 gene cause Hennekam lymphangiectasia-lymphedema syndrome (PMID: 19935664).