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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
24449-1-PBS targets CCBE1 in IHC, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CCBE1 fusion protein Ag19686 相同性解析による交差性が予測される生物種 |
| Full Name | collagen and calcium binding EGF domains 1 |
| Calculated molecular weight | 406 aa, 44 kDa |
| GenBank accession number | BC046645 |
| Gene Symbol | CCBE1 |
| Gene ID (NCBI) | 147372 |
| RRID | AB_2879553 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q6UXH8 |
| Storage Buffer | PBS only , pH 7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
CCBE1 (collagen and calcium-binding EGF domain-containing protein 1) is a secreted protein that is indispensible for lymphangiogenesis during development. CCBE1 may be a guidance molecule that regulates lymphangioblast budding and possibly migration (PMID: 19287381). The gene of CCBE1 maps to 18q21.32 and encodes a protein of 44 kDa that contains an EGF-like domain and two collagen-like domains. Mutations in the CCBE1 gene cause Hennekam lymphangiectasia-lymphedema syndrome (PMID: 19935664).