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  • KD/KO Validated

CCNY Polyclonal antibody

CCNY Polyclonal Antibody for WB, IF/ICC, IP, ELISA
Cat No. 18042-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, IP, ELISA

Cyclin fold protein 1, Cyclin box protein 1, Cyc Y, CFP1, CBCP1

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inA549 cells, K-562 cells
Positive IP detected inK-562 cells
Positive IF/ICC detected inA549 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

18042-1-AP targets CCNY in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CCNY fusion protein Ag12674 相同性解析による交差性が予測される生物種
Full Name cyclin Y
Calculated molecular weight 33 kDa, 39 kDa
Observed molecular weight 33-39 kDa
GenBank accession numberBC104773
Gene Symbol CCNY
Gene ID (NCBI) 219771
RRIDAB_2074004
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8ND76
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CCNY, also named as C10orf9, CBCP1, CFP1, is a novel cyclin. CCNY acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway.

Protocols

Product Specific Protocols
WB protocol for CCNY antibody 18042-1-APDownload protocol
IF protocol for CCNY antibody 18042-1-APDownload protocol
IP protocol for CCNY antibody 18042-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratWB

Prog Neurobiol

Cyclin Y, a novel actin-binding protein, regulates spine plasticity through the cofilin-actin pathway.

Authors - Hongik Hwang
human,mouseWB,IP

Prog Neurobiol

Myristoylation-dependent palmitoylation of cyclin Y modulates long-term potentiation and spatial learning

Authors - Jiyeon Seo
mouseWB

Pharmacol Res

Ccny knockout mice display an enhanced susceptibility to kainic acid-induced epilepsy.

Authors - Hongik Hwang
  • KO Validated
mouseWB

Biochem J

Cyclin Y phosphorylation- and 14-3-3-binding-dependent activation of PCTAIRE-1/CDK16.

Authors - Saifeldin N Shehata
humanWB,IF

Cells

The Candidate IBD Risk Gene CCNY Is Dispensable for Intestinal Epithelial Homeostasis.

Authors - Andrea Molinas
mouseWB, IP

Cell Signal

Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase.

Authors - Shehata Saifeldin N SN
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