Mouse CD163 Recombinant antibody, PBS Only (Capture/Detector)
CD163 Recombinant Antibody for Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test
Host / Isotype
Rabbit / IgG
Reactivity
mouse
Applications
Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test
Conjugate
Unconjugated
CloneNo.
240233F4
Cat no : 83285-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
83285-1-PBS targets CD163 as part of a matched antibody pair:
MP00326-1: 83285-2-PBS capture and 83285-1-PBS detection (validated in Cytometric bead array)
MP00326-3: 83285-1-PBS capture and 83285-2-PBS detection (validated in Sandwich ELISA)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
Tested Reactivity | mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Fusion Protein 相同性解析による交差性が予測される生物種 |
Full Name | CD163 antigen |
Calculated molecular weight | 121 kDa |
GenBank accession number | NM_053094.2 |
Gene symbol | Cd163 |
Gene ID (NCBI) | 93671 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CD163, also known as M130, is a membrane glycoprotein that belongs to the scavenger receptor superfamily (PMID: 8370408). It is an acute phase-regulated and signal-inducing macrophage protein expressed exclusively in monocytes and tissue macrophages (PMID: 11196644). CD163 mediates endocytosis of haptoglobin-haemoglobin complexes (PMID: 11196644). The uptake of haptoglobin by macrophages contributes to the recycling of iron and also to the inflammatory response (PMID: 22900885). Soluble CD163 (sCD163), as a result of ectodomain shedding during inflammatory activation of macrophages, circulates in blood and has been suggested as a plasma/serum marker for macrophage activity (PMID: 12570164).