Anti-Human CD18 (TS1/18) Mouse IgG1 Recombinant Antibody, PBS Only
CD18 Recombinant Antibody for FC
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
FC
Conjugate
Unconjugated
CloneNo.
TS1/18
Cat no : 65524-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
| Positive FC detected in | human PBMCs |
Recommended dilution
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
65524-1-PBS targets CD18 in FC applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Human Beta 2 Integrin 相同性解析による交差性が予測される生物種 |
| Full Name | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| Calculated molecular weight | 85 kDa |
| GenBank accession number | BC005861 |
| Gene symbol | CD18 |
| Gene ID (NCBI) | 3689 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Affinity purification |
| Storage Buffer | PBS only |
| Storage Conditions | Store at -80°C. Stable for one year after shipment. |
Background Information
CD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a/CD18 (LFA-1) is expressed by all leukocytes, while CD11b/CD18 (Mac-1) and CD11c/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570).
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for CD18 antibody 65524-1-PBS | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
