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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CD1c Polyclonal antibody

CD1c Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 28838-1-AP

Synonyms

T-cell surface glycoprotein CD1c, R7, CD1c molecule, CD1, BDCA1

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using CD1c Polyclonal antibody (28838-1-AP)

    IHC staining of human tonsillitis using 28838-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 28838-1-AP (CD1c antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using CD1c Polyclonal antibody (28838-1-AP)

    IHC staining of human tonsillitis using 28838-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 28838-1-AP (CD1C antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Tested Applications

Positive IHC detected inhuman tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

28838-1-AP targets CD1c in IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CD1c fusion protein Ag29830 相同性解析による交差性が予測される生物種
Full Name CD1c molecule
Calculated molecular weight 333 aa, 38 kDa
GenBank accession numberBC126467
Gene symbol CD1C
Gene ID (NCBI) 911
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CD1c molecule (CD1c, also known as R7, CD1, CD1A, and BDCA1) is a member of the CD1 family of transmembrane glycoproteins, which synthesizes in the endoplasmic reticulum and expresses on the monocytes, marginal zone B cells in lymph nodes as well as peripheral blood (PMID: 23468110). The CD1 proteins belong to the family of major histocompatibility complex (MHC) class I-like proteins that present lipid-based antigens to T cells (PMID: 15032598; 23127489). CD1c shows interaction with both αβ or γδ T cells and mediates T cell responses against mycobacterium tuberculosis (PMID: 10727456; 10786796).

Protocols

Product Specific Protocols
IHC protocol for CD1c antibody 28838-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols