CD206 Recombinant antibody, PBS Only
CD206 Recombinant Antibody for WB, IHC, IF-P, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, pig
Applications
WB, IHC, IF-P, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1G15
Cat no : 81525-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
81525-1-PBS targets CD206 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.
Tested Reactivity | human, mouse, pig |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
Full Name | mannose receptor, C type 1 |
Calculated molecular weight | 166 kDa |
Observed molecular weight | 170 kDa |
GenBank accession number | NM_002438 |
Gene symbol | CD206 |
Gene ID (NCBI) | 4360 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.