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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

Anti-Human CD209 Rabbit Recombinant Antibody, PBS Only

CD209 Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

240907A4

Cat no : 98156-1-PBS

Synonyms

DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN

Validation Data Gallery

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  • Flow cytometry (FC) experiment of human monocyte-derived immature dendritic cells using Anti-Human CD209 Rabbit Recombinant Antibody (98156-1-RR)

    FC experiment of human monocyte-derived immature dendritic cells using 98156-1-RR (same clone as 98156-1-PBS)

    1x10^6 human monocyte-derived immature dendritic cells were surface stained with 0.25 ug Anti-Human CD209 Rabbit Recombinant Antibody (98156-1-RR, Clone: 240907A4) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98156-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98156-1-RR

    Affinity and Kinetic Characterization of 98156-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98156-1-RR against Human CD209 were performed. The affinity constant is 1.94 nM.

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Tested Applications

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

The immunogen of 98156-1-PBS is CD209 Fusion Protein expressed in E. coli.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Fusion Protein 相同性解析による交差性が予測される生物種
Full Name CD209 molecule
Calculated molecular weight 404 aa, 45.7 kDa
GenBank accession numberBC110615
Gene symbol CD209
Gene ID (NCBI) 30835
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).