• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
×

Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CD38 Recombinant antibody, PBS Only

CD38 Recombinant Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241246D5

Cat no : 84070-6-PBS

Synonyms

ADPRC 1, ADP ribosyl cyclase 1, 2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of various lysates using CD38 Recombinant antibody (84070-6-RR)

    WB analysis using 84070-6-RR (same clone as 84070-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84070-6-RR (CD38 antibody) at dilution of 1:17000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84070-6-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using CD38 Recombinant antibody (84070-6-RR)

    IHC staining of human tonsillitis using 84070-6-RR (same clone as 84070-6-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84070-6-RR (CD38 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84070-6-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using CD38 Recombinant antibody (84070-6-RR)

    IHC staining of human tonsillitis using 84070-6-RR (same clone as 84070-6-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84070-6-RR (CD38 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84070-6-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of Raji cells using CD38 Recombinant antibody (84070-6-RR)

    IF Staining of Raji using 84070-6-RR (same clone as 84070-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Raji cells using CD38 antibody (84070-6-RR, Clone: 241246D5 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84070-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84070-6-RR

    Affinity and Kinetic Characterization of 84070-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84070-6-RR against Human CD38 were performed. The affinity constant is 1.11 nM.

☆大好評トライアルサイズ ¥20,000～！ >>> 一次抗体特別価格キャンペーン開催中！

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

The immunogen of 84070-6-PBS is CD38 Fusion Protein expressed in E. coli.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Fusion Protein 相同性解析による交差性が予測される生物種
Full Name CD38 molecule
Calculated molecular weight 300 aa, 34 kDa
Observed molecular weight45 kDa
GenBank accession numberBC007964
Gene symbol CD38
Gene ID (NCBI) 952
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).