CoraLite® Plus 488 Anti-Human CD38 (HB7)
CD38 Monoclonal Antibody for IF, FC
Host / Isotype
Mouse / IgG1, kappa
Reactivity
Human
Applications
IF, FC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
HB7
Cat no : CL488-65107
Synonyms
Validation Data Gallery
Tested Applications
| Positive IF/ICC detected in | human peripheral blood mononuclear cells |
| Positive FC detected in | human peripheral blood lymphocytes |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
CL488-65107 targets CD38 in IF, FC applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Human BJAB B cell line 相同性解析による交差性が予測される生物種 |
| Full Name | CD38 molecule |
| Calculated molecular weight | 300 aa, 34 kDa |
| GenBank accession number | BC007964 |
| Gene symbol | CD38 |
| Gene ID (NCBI) | 952 |
| RRID | AB_2883181 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Background Information
CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 CD38 antibody CL488-65107 | Download protocol |
| FC protocol for CL Plus 488 CD38 antibody CL488-65107 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
