Anti-Rat CD45RA (OX-33) Mouse IgG2a Recombinant Antibody, PBS Only

CD45RA Recombinant Antibody for FC

Host / Isotype

Mouse / IgG2a

Reactivity

rat

Applications

FC

Conjugate

Unconjugated

CloneNo.

OX-33

Cat no : 65578-1-PBS

Synonyms

Lca, Ptprc, CD45, RT7, OX-33


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Tested Applications

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

65578-1-PBS targets CD45RA in FC applications and shows reactivity with rat samples.

Tested Reactivity rat
Host / Isotype Mouse / IgG2a
Class Recombinant
Type Antibody
Immunogen Leukocyte common antigen purified from rat splenocytes 相同性解析による交差性が予測される生物種
Full Name protein tyrosine phosphatase, receptor type, C
Calculated molecular weight143 kDa
GenBank accession numberXM_006249910
Gene symbol CD45
Gene ID (NCBI) 24699
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signaling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RA is expressed on naïve T cells, B cells, and monocytes (PMID: 1830500; 14687231).