Anti-Human CD45RO (UCHL1) Mouse IgG2a Recombinant Antibody, PBS Only
CD45RO Recombinant Antibody for IHC, FC
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
IHC, FC
Conjugate
Unconjugated
CloneNo.
UCHL1
Cat no : 65613-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
65613-1-PBS targets CD45RO in IHC, FC applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2a |
Class | Recombinant |
Type | Antibody |
Immunogen | IL-2 dependent T cell line, CA1 相同性解析による交差性が予測される生物種 |
Full Name | protein tyrosine phosphatase, receptor type, C |
GenBank accession number | BC014239 |
Gene symbol | CD45 |
Gene ID (NCBI) | 5788 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RO is the shortest CD45 isoform (lacking all three exons) and is expressed by activated and memory T cells, thymocytes, some B cells, and weakly on granulocytes and macrophage (PMID: 27100180; 12414720).